肖炜


副研究员/ weixiao@ynu.edu.cn/病毒生态学,噬菌体制剂创制



主要研究方向:

噬菌体制剂的开发与应用;高盐环境、湖泊微生物(噬菌体)多样性和生态功能;噬菌体-宿主相互作用的动态变化及其影响因素和机制。


教育经历:

1. 2006/9–2009/7,中山大学,获博士学位

2. 2003/9–2006/7,云南大学,获硕士学位

3.1998/9–2002/7,河北大学,获学士学位


获奖及人才计划

1.罗开珺,李明,肖炜,杨洋,刘甜. 双斑侧沟茧蜂病毒免疫抑制机制,2020年度云南省自然科学二等奖。

2.云南省万人计划“青年拔尖人才”,2018-2023。

3.云南省科技特派员,2014

4.云南大学“东陆中青年骨干教师”培养计划培养对象,2016.12-2019.12


主持的主要科研项目:

1.湖泊富营养化对浮游病毒与宿主相互关系的影响及机理研究,国家自然科学基金面上项目,58万,2021.1-2024.12

2.高原富营养化湖泊浮游病毒多样性及其对藻类群落的调控,国家自然科学基金地区基金,38万,2017.1-2020.12

3.古老岩盐沉积中的噬菌体多样性及其基因组和宿主域研究,国家自然科学基金青年基金, 23万,2013.01-2015.12

4.云南省微生物资源与系统学公共服务平台建设和技术研发,中央引导地方科技发展专项资金,100万,2018

5.南亚东南亚特色微生物资源保护与利用合作研究基地,云南省重点研发计划项目 (国际科技合作), 100万,2018-2021

6.石林喀斯特碳酸盐矿化菌多样性及其在石材保护中的应用,云南省应用基础研究项目,10万,2014.10-2017.10



代表性论著(第一作者和通讯作者):

1. Diao Kaixin, Li Guohui, Sun Xueqin, Yi Hao , Zhang Shiying,Xiao Wei #. Genomic characterization of a halovirus representing a novel siphoviral cluster. Viruses-Basel. 2023, 15(6), 1392.

2.Yi Hao, Fu Chaoqun, Diao Kaixin, Li Zhiying, Cui Xiaolong*,Xiao Wei*. Characterization and genomic analysis of a novel halovirus infectingChromohalobacter beijerinckii. Front. Microbiol. 2022, 13:1041471.

3.CheRaoqiong,BaiMeng,XiaoWei*,ZhangShiying,WangYongxia,CuiXiaolong*.Nutrient levels and prokaryotes affect viral communities in plateau lakes,Science of The Total Environment,2022,839:156033.

4.Cheng Yahui, Gao Dongye, Xia Yunsheng, Wang Ziyi, Bai Meng, Luo Kaijun, Cui Xiaolong, Wang Yongxia, Zhang Shiying*,Xiao Wei*.Characterization of Novel Bacteriophage AhyVDH1 and Its Lytic Activity AgainstAeromonas hydrophila,Curr Microbiol, 2021,78: 329–337.

5.Bai Meng, Cheng Ya-Hui, Sun Xue-Qin, Wang Zi-Yi, Wang Yong-Xia, Cui Xiao-Long*,Xiao Wei*. Nine Novel Phages from a Plateau Lake in Southwest China: Insignts into Aeromonas Phages Diversity. Viruses-Basel, 2019, 11: 615.

6.Cui, J.-H.#, Dong, S.-M.#, Chen, C.-X.#,Xiao, W.#, Cai, Q.-C., Zhang, L.-D., He, H.-J., Zhang, W., Zhang, X.-W., Liu, T., Ding, L., Yang, Y., Lai, J.-H., Zhu, Q.-S., Luo, K.-J..Microplitis bicoloratusbracovirus modulates innate immune suppression through the eIF4E-eIF4A axis in the insectSpodoptera litura. Dev. Comp. Immunol.2019, 95:101-107.

7.Zhang Shiying, Fan Cong, Xia Yunsheng, Li Mengke, Wang Yongxia, Cui Xiaolong,Xiao Wei*.Characterization of a novel bacteriophage specific toExiguobacterium indicumisolated from a plateau eutrophic lake. J Basic Microbiol. 2019, 59206-214.

8.Zhang Shiying#,Fan Cong#,Wang Yongxia,Xia Yunsheng,Xiao Wei*, Cui Xiaolong*.Salt-tolerant and plant growth-promoting bacteria isolated from high-yield paddy soil.Canadian Journal of Microbiology, 2018,64(12): 968-978.

9.Fu ChaoqunZhao QinLi ZhiyingWang YongxiaZhang ShiyingLai YonghongXiao Wei*, Cui Xiaolong*. Complete genome sequence ofHalomonas ventosaevirulent halovirus QHHSV-1. Arch Virol, 2017, 162(10): 3215-3219.

10.Chen Ya-Bin#,Xiao Wei#, Li Ming#, Zhang Yan, Yang Yang, Hu Jian-Sheng, Luo Kai-Jun*.N-terminally elongated SpliInx2 and SpliInx3 reduce baculovirus-triggereapoptosis, via hemichannel closure.Archives of Insect Biochemistry & Physiology, 201692(1):24–37.

11.Fu Chao-Qun, Zhao Qin, Li Zhi-Ying, Wang Yong-Xia, Zhang Shi-Ying , Lai Yong-Hong,Xiao Wei*, Cui Xiao-Long*.A novelHalomonas ventosae-specific virulent halovirus isolated from the Qiaohou salt mine in Yunnan, Southwest China.Extremophiles, 2016, 20(1): 101-110.

12.Zhang Shi-Ying#,Xiao Wei#, Xia Yun-Sheng, Wang Yong-Xia, Cui Xiao-Long*, Zhang Nai-Ming*.Arenimonas taoyuanensissp. nov., a novel bacterium isolatedfrom rice-field soil in China.Antonie van Leeuwenhoek.2015, 1075), 1181-1187.

13.Li Ming#, Pang Zunyu#,Xiao Wei#, Liu Xinyi, Zhang Yan, Yu Dongshuai, Yang Minjun, Yang Yang, Hu Jiansheng, Luo Kaijun. A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes ofSpodoptera lituraafter parasitization byMicroplitis bicoloratusPLoS ONE 2014,9(10): e110967.

14.Wang Yong-Xia#,Xiao Wei#, Dong Ming-Hua, Zhao Qin, Li Zhi-Ying, Lai Yong-Hong, Cui Xiao-Long. 2014.Halomonas qiaohouensissp. nov., isolated from salt mine soil in southwest China.Antonie van Leeuwenhoek, 2014, 106(2): 253-260.

15.Xiao Wei, Wang Zhigang; Wang yongxia; Schneegurt Mark A.; Li Zhiying; Lai Yonghong; Zhang Shiying; Wen Mengliang; Cui Xiaolong*. Comparative molecular analysis of the prokaryotic diversity of two salt mine soils in southwest China.J Basic Microbiol,2013, 53(11): 942-952.

16.Zhao Ming#,Xiao Wei#, Ma Yan ,Sun Tingting, Yuan Wenxia, Tang Na, Zhang Donglian, Wang Yongxia, Li Yali, Zhou Hongjie, Cui XiaolongStructure and dynamics of the bacterial communities in fermentation of the traditional Chinese post-fermented pu-erh tea revealed by 16S rRNA gene clone library, World J Microbiol Biotechnol,2013, 29(10): 1877-1884.

17.Xiao Wei, Wang Yongxia., Liu Jihui, Wang Zhigang, Zhang Xiaoxia, Ji Kaiyan, Lai Yonghong, Wen Mengliang, Cui Xiaolong.Roseivivax sediminissp. nov., a moderately halophilic bacterium isolated from salt mine sediment.Int J Syst Evol Microbiol. 2012, 62, 1890–1895.

18.Xiao Wei., Yang Yi, Weng QingBei, Yuan, MeiJin, Yang Kai, Pang Yi.The role of the PI3K-Akt signal transduction pathway inAutographa californica multiple nucleopolyhedrovirusinfection ofSpodoptera frugiperdacells.Virology. 2009, 391: 83-89.

19.肖炜,张仕颖,赵琴,王永霞,赖泳红,李治滢,崔晓龙,云南个旧锡矿区可培养细菌多样性及其重金属抗性,微生物学报,2013,53(11):1158-1165.

20.赵琴,任鹏康,王永霞,李治滢,吴鸣,肖炜*,崔晓龙*。云南盐矿中病毒样颗粒的多样性,微生物学报,2015,55(10):1327-1335.

21.傅超群,白萌,王永霞,李治滢,赖泳红,肖炜*,崔晓龙*。高盐环境可培养细菌噬菌体的研究进展,微生物学通报,2017,44(4):920-928。

22.张仕颖,董星凡,王永霞,李治滢,赖泳红,崔晓龙,肖炜*。石林喀斯特碳酸钙高效沉积菌的筛选及其沉积条件优化。云南大学学报(自然科学版),2018,40(3):568-576。

23.李孟珂,夏运生,单壮壮,姬桐,崔晓龙,肖炜*,张仕颖*。三株蓝藻附着细菌多样性及其对铜绿微囊藻增殖的影响,云南大学学报(自然科学版), 2019, (06): 1238-1245.

24.张俊锋,李孟珂,吴志浩,崔晓龙,肖炜*,张仕颖*,噬菌体 DCEAV-31 和 DCEIV-9 对溶藻菌溶藻特性的影响,生物技术通报. 2022,38(11):250-257

25.参编《环境土壤学》(张乃明 主编,中国农业大学出版社,北京,2013. [普通高等教育“十二五”规划建设教材])

26.参编《云南微生物资源与名录》(张克勤,余泽芬主编,科学出版社,北京,2022)



授权或申请发明专利

(1)肖炜,崔晓龙,赵琴,王永霞,一种提高微生物可培养性的装置,ZL 201320247504.4。

(2)肖炜,张仕颖,成亚辉,钟莉瑶,王永霞,崔晓龙。一种噬菌体及其应用,201911093070.5。


教学获奖情况

1. 指导的项目“噬枯灵——高效环保的微生物农药”获第六届中国国际“互联网+”大学生创新创业大赛校级决赛银奖(2020.7)。

2. 荣获第15届云南大学教师课堂教学比赛优秀奖(2021.11)。

3. 指导的项目“校园不同污水处理厂病毒多样性比较研究”获全国大学生生命科学竞赛(2022,科学探究类)云南赛区二等奖。

4. 指导的项目“校园不同污水处理厂病毒多样性比较研究”获全国大学生生命科学竞赛(2022,科学探究类)国赛三等奖。

5. 指导的项目“菌立噬-高效安全的噬菌体制剂领航者”获云南大学第九届“互联网+”创新创业大赛创意组金奖(2023.8)。


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